“Justin Chambers Shares Rare Insight into Life Raising Four Daughters”
Izzie Stevens faced cancer, married Alex, survived the illness, and then seemingly disappeared in season six. She later returned and confessed that she no longer felt like Seattle was her home. Subsequently, Alex received divorce papers, revealing that Izzie had secretly given birth to their twins and was now living on a ranch in Kansas, working as a surgical oncologist.
Katherine Heigl‘s departure began in 2008 when she withdrew her name from Emmy consideration, feeling that the material did not warrant it. The character disappeared entirely in 2010. Despite expressing a desire to return to the role in subsequent years, Shonda Rhimes declined. “I’m done with that story,” Rhimes told TVLine in 2015.
Following her departure, Heigl continued to star in romantic comedies before returning to television with State of Affairs, then Doubt, and more recently, joining Suits and the 2020 series Firefly Lane.